Tuesday, December 06, 2005

Everything you wanted to know about swallowing....


Stumbled on a medical journal today and found the most interesting information about oral sex. Ladies and Gentlemen... (Drum roll) It is my wonderful pleasure (Funny how I like saying that word) to announce that there is a benefit to swallowing rather than spitting during oral sex.

Now seriously, if you think I am a sick weird pervert who spends his hard-working days in front of the computer all day and does nothing but "fill-in-the-blank" off all day. I am sorry if I disappoint you with my perhaps educational journal entry.

Well, here is the Holy Grail:

Correlation between oral sex and a low incidence of preeclampsia: a role for soluble HLA in seminal fluid?

Yes, here I had found a paper that proved once and for all that there was an actual health benefit to swallowing. I read on and discovered the abstract:

The involvement of immune mechanisms in the aetiology of preeclampsia is often suggested. Normal pregnancy is thought to be associated with a state of tolerance to the foreign antigens of the fetus, whereas in preeclamptic women this immunological tolerance might be hampered. The present study shows that oral sex and swallowing sperm is correlated with a diminished occurrence of preeclampsia which fits in the existing idea that a paternal factor is involved in the occurrence of preeclampsia. Because pregnancy has many similarities with transplantation, we hypothesize that induction of allogeneic tolerance to the paternal HLA molecules of the fetus may be crucial. Recent data suggest that exposure, and especially oral exposure to soluble HLA (sHLA) or HLA derived peptides can lead to transplantation tolerance. Similarly, sHLA antigens, that are present in the seminal plasma, might cause tolerance in the mother to paternal antigens. In order to test whether this indeed may be the case, we investigated whether sHLA antigens are present in seminal plasma. Using a specific ELISA we detected sHLA class I molecules in seminal plasma. The level varied between individuals and was related to the level in plasma. Further studies showed that these sHLA class I molecules included classical HLA class I alleles, such as sHLA-A2, -B7, -B51, -B35 and sHLA-A9. Preliminary data show lower levels of sHLA in seminal plasma in the preeclampsia group, although not significantly different from the control group. An extension of the present study is necessary to verify this hypothesis.

Well ladies I am ready and happy to contribute for the benefit of medical research.